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ELK Biotechnology
SKU(재고 관리 코드):ES11345
SPRE1 Rabbit Polyclonal Antibody
SPRE1 Rabbit Polyclonal Antibody
SPRE1 Rabbit Polyclonal Antibody
Overview
| Product name: | SPRE1 rabbit pAb |
| Applications: | WB;ELISA |
| Recommended Dilutions: | WB 1:500-2000 ELISA 1:5000-20000 |
| Immunogen: | Synthesized peptide derived from human protein . at AA range: 210-290 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 48kD |
| GeneID(Human): | 161742 |
| Human Swiss-Prot No: | Q7Z699 |
| Cellular localization: | Cell membrane ; Peripheral membrane protein . Membrane, caveola ; Peripheral membrane protein . Nucleus . Localized in cholesterol-rich membrane raft/caveola fractions. |
| Background: | The protein encoded by this gene is a member of the Sprouty family of proteins and is phosphorylated by tyrosine kinase in response to several growth factors. The encoded protein can act as a homodimer or as a heterodimer with SPRED2 to regulate activation of the MAP kinase cascade. Defects in this gene are a cause of neurofibromatosis type 1-like syndrome (NFLS). [provided by RefSeq, Jul 2008], |
| Species Reactivity: | Human;Mouse |
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