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ELK Biotechnology

SKU(재고 관리 코드):ES11345

SPRE1 Rabbit Polyclonal Antibody

SPRE1 Rabbit Polyclonal Antibody

Size

SPRE1 Rabbit Polyclonal Antibody

Overview

Product name: SPRE1 rabbit pAb
Applications: WB;ELISA
Recommended Dilutions: WB 1:500-2000 ELISA 1:5000-20000
Immunogen: Synthesized peptide derived from human protein . at AA range: 210-290
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 48kD
GeneID(Human): 161742
Human Swiss-Prot No: Q7Z699
Cellular localization: Cell membrane ; Peripheral membrane protein . Membrane, caveola ; Peripheral membrane protein . Nucleus . Localized in cholesterol-rich membrane raft/caveola fractions.
Background: The protein encoded by this gene is a member of the Sprouty family of proteins and is phosphorylated by tyrosine kinase in response to several growth factors. The encoded protein can act as a homodimer or as a heterodimer with SPRED2 to regulate activation of the MAP kinase cascade. Defects in this gene are a cause of neurofibromatosis type 1-like syndrome (NFLS). [provided by RefSeq, Jul 2008],
Species Reactivity: Human;Mouse
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