SPTA1 Rabbit Polyclonal Antibody

Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton| and functions in the determination of cell shape| arrangement of transmembrane proteins| and organization of organelles. It is a tetramer made up of alpha-beta dimers linked in a head-to-head arrangement. This gene is one member of a family of alpha-spectrin genes. The encoded protein is primarily composed of 22 spectrin repeats which are involved in dimer formation. It forms weaker tetramer interactions than non-erythrocytic alpha spectrin| which may increase the plasma membrane elasticity and deformability of red blood cells. Mutations in this gene result in a variety of hereditary red blood cell disorders| including elliptocytosis type 2| pyropoikilocytosis| and spherocytic hemolytic anemia.

The SPTA1 Rabbit Polyclonal Antibody is a highly specific and sensitive antibody designed for use in various research applications. This antibody is produced using high-quality rabbit polyclonal immunoglobulin G (IgG) and is purified using a proprietary process to ensure maximum purity and specificity. The SPTA1 Rabbit Polyclonal Antibody is specifically designed to target the spectrin alpha chain, which is a cytoskeletal protein that plays a critical role in maintaining the structural integrity of red blood cells. This antibody has been extensively validated for use in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. With its high specificity and sensitivity, the SPTA1 Rabbit Polyclonal Antibody is an ideal tool for researchers studying the role of spectrin alpha chain in various biological processes.