SQSTM1/p62(Phospho-Thr269/Ser272) Rabbit Polyclonal Antibody

This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone.

The SQSTM1/p62(Phospho-Thr269/Ser272) Rabbit Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of SQSTM1/p62 protein phosphorylated at Thr269 and Ser272 residues. This antibody is produced using high-quality rabbit polyclonal antibodies, ensuring reliable and reproducible results.

SQSTM1/p62 is a multifunctional protein involved in various cellular processes, including autophagy, inflammation, and signal transduction. Phosphorylation of SQSTM1/p62 at Thr269 and Ser272 has been implicated in the regulation of its function and interaction with other proteins. Therefore, the ability to detect and quantify the phosphorylation status of SQSTM1/p62 is crucial for understanding its role in cellular processes and disease pathogenesis.

The SQSTM1/p62(Phospho-Thr269/Ser272) Rabbit Polyclonal Antibody exhibits high specificity towards the phosphorylated form of SQSTM1/p62, with minimal cross-reactivity to non-phosphorylated SQSTM1/p62 or other proteins. This antibody has been extensively validated in various experimental settings, including Western blotting, immunoprecipitation, and immunofluorescence, ensuring its reliability and accuracy.

With its exceptional sensitivity and specificity, the SQSTM1/p62(Phospho-Thr269/Ser272) Rabbit Polyclonal Antibody is an indispensable tool for researchers studying autophagy, inflammation, and signal transduction pathways. Its application in various techniques allows for comprehensive analysis of SQSTM1/p62 phosphorylation, enabling a deeper understanding of its functional implications in cellular processes and disease mechanisms.

Order the SQSTM1/p62(Phospho-Thr269/Ser272) Rabbit Polyclonal Antibody today and unlock new insights into the intricate regulatory mechanisms of SQSTM1/p62 protein.