SRY (Acetyl Lys136) Rabbit Polyclonal Antibody

disease:Defects in SRY are a cause of gonadal dysgenesis XY female type (GDXY)

The SRY (Acetyl Lys136) Rabbit Polyclonal Antibody is a highly specific and sensitive immunological reagent designed for the detection and quantification of SRY protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the acetylated lysine 136 of the SRY protein. The antibody has been purified using affinity chromatography and validated for its specificity and sensitivity by various immunoassays, including Western blotting, immunoprecipitation, and immunofluorescence.

The SRY protein is a transcription factor that plays a critical role in male sex determination and differentiation. Mutations or dysregulation of SRY expression have been associated with various disorders of sexual development and infertility. Therefore, the SRY (Acetyl Lys136) Rabbit Polyclonal Antibody is a valuable tool for researchers and clinicians studying the molecular mechanisms of sex determination and related disorders.

This antibody is supplied as a liquid formulation in phosphate-buffered saline (PBS) with 0.02% sodium azide as a preservative. It is suitable for use in various applications, including immunohistochemistry, flow cytometry, and ELISA. The recommended working dilution for this antibody is 1:1000 for Western blotting and 1:200 for immunofluorescence. The antibody has a high affinity and specificity for the acetylated lysine 136 of the SRY protein and does not cross-react with other related proteins.

In summary, the SRY (Acetyl Lys136) Rabbit Polyclonal Antibody is a reliable and sensitive tool for the detection and quantification of SRY protein in various biological samples. Its high specificity and sensitivity make it an ideal reagent for researchers and clinicians studying the molecular mechanisms of sex determination and related disorders.