SSX2 Rabbit Polyclonal Antibody

The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneous humoral and cellular immune responses in cancer patients| and are potentially useful targets in cancer vaccine-based immunotherapy. This gene| and also the SSX1 and SSX4 family members| have been involved in t(X;18)(p11.2;q11.2) translocations that are characteristically found in all synovial sarcomas. This translocation results in the fusion of the synovial sarcoma translocation gene on chromosome 18 to one of the SSX genes on chromosome X. The encoded hybrid proteins are likely responsible for transforming activity. Alternative splicing of this gene results in multiple transcript variants. This gene also has an identical duplicate| GeneID: 727837| located about 45 kb downstream in the opposite orientation on chromosome X.

The SSX2 Rabbit Polyclonal Antibody is a highly specific and sensitive antibody designed for the detection of SSX2 protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human SSX2 protein. The resulting antibody has been purified using protein A affinity chromatography and validated for its specificity and sensitivity through various assays.

The SSX2 Rabbit Polyclonal Antibody is suitable for use in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It has been shown to detect endogenous SSX2 protein in human cell lines and tissues, making it an ideal tool for studying the expression and function of SSX2 in various biological contexts.

This antibody is supplied as a liquid formulation in phosphate-buffered saline (PBS) with 0.02% sodium azide as a preservative. It is available in various sizes to meet the needs of different research projects. The SSX2 Rabbit Polyclonal Antibody is a reliable and high-quality reagent that can help researchers advance their understanding of SSX2 biology.