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ELK Biotechnology

ES1460

Synaptotagmin 1/2 (phospho Ser309/306) Rabbit Polyclonal Antibody

Synaptotagmin 1/2 (phospho Ser309/306) Rabbit Polyclonal Antibody

Size

Synaptotagmin 1/2 (phospho Ser309/306) Rabbit Polyclonal Antibody

Overview

Product name: Synaptotagmin 1/2 (phospho Ser309/306) rabbit pAb
Alternative Names: SYT1; SVP65; SYT; Synaptotagmin-1; Synaptotagmin I; SytI; p65; SYT2; Synaptotagmin-2; Synaptotagmin II; SytII
Applications: WB;IHC;IF;ELISA
Recommended Dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human Synaptotagmin around the phosphorylation site of Ser309. AA range:276-325
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 47kD
GeneID（Human）: 6857/127833
Human Swiss-Prot No: P21579/Q8N9I0
Cellular localization: Cytoplasmic vesicle, secretory vesicle membrane ; Single-pass membrane protein . Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane ; Single-pass membrane protein . Cytoplasmic vesicle, secretory vesicle, chromaffin granule membrane ; Single-pass membrane protein . Cytoplasm .
Background: The synaptotagmins are integral membrane proteins of synaptic vesicles thought to serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. Calcium binding to synaptotagmin-1 participates in triggering neurotransmitter release at the synapse (Fernandez-Chacon et al., 2001 [PubMed 11242035]).[supplied by OMIM, Jul 2010],
Species Reactivity: Human;Mouse;Rat
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