Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Immunogen:
The antiserum was produced against synthesized peptide derived from human SYT11. AA range:181-230
Storage:
Rabbit
Storage:
-20°C/1 year
Clonality:
Polyclonal
Isotype:
IgG
Concentration:
1 mg/ml
Observed Band:
48kD
GeneID（Human）:
23208
Human Swiss-Prot No:
Q9BT88
Cellular localization:
Cytoplasmic vesicle membrane ; Single-pass membrane protein . Perikaryon . Golgi apparatus, trans-Golgi network membrane ; Single-pass membrane protein . Recycling endosome membrane ; Single-pass membrane protein . Lysosome membrane ; Single-pass membrane protein . Cytoplasmic vesicle, phagosome . Cell projection, axon . Cell projection, dendrite . Cell junction, synapse, postsynaptic density . Recycling endosome membrane ; Single-pass membrane protein . Cytoplasmic vesicle, clathrin-coated vesicle membrane ; Single-pass membrane protein . Perikaryon . Localized in vesicles that travels in axonal and dendritic shafts in both anterograde and retrograde directions. In macrophages and microglia, recruited in phagosomes at early stages of phagocytosis (By similarity). Found in the core of the
Background:
synaptotagmin 11(SYT11) Homo sapiens This gene is a member of the synaptotagmin gene family and encodes a protein similar to other family members that are known calcium sensors and mediate calcium-dependent regulation of membrane trafficking in synaptic transmission. The encoded protein is also a substrate for ubiquitin-E3-ligase parkin. The gene has previously been referred to as synaptotagmin XII but has been renamed synaptotagmin XI to be consistent with mouse and rat official nomenclature. [provided by RefSeq, Apr 2010],
