TAK1(Phospho-Ser412) Rabbit Polyclonal Antibody

The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP)| and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1| this protein forms a kinase complex including TRAF6| MAP3K7P1/TAB1 and MAP3K7P2/TAB2; this complex is required for the activation of nuclear factor kappa B. This kinase can also activate MAPK8/JNK| MAP2K4/MKK4| and thus plays a role in the cell response to environmental stresses. Four alternatively spliced transcript variants encoding distinct isoforms have been reported.

Introducing the TAK1(Phospho-Ser412) Rabbit Polyclonal Antibody, a highly specific and reliable tool for the detection and analysis of TAK1 protein phosphorylated at Serine 412. This antibody is meticulously developed using advanced rabbit polyclonal technology, ensuring exceptional sensitivity and accuracy in various applications.

The TAK1(Phospho-Ser412) Rabbit Polyclonal Antibody exhibits outstanding specificity towards the phosphorylated form of TAK1 at Serine 412, making it an invaluable asset for researchers investigating the intricate signaling pathways involving TAK1. With its exceptional affinity and selectivity, this antibody enables precise identification and quantification of TAK1 phosphorylation events, facilitating comprehensive understanding of cellular processes and disease mechanisms.

This antibody is meticulously validated through rigorous quality control measures, guaranteeing optimal performance and reproducibility. Its superior sensitivity allows for the detection of even low abundance phosphorylated TAK1, enabling researchers to obtain accurate and reliable results. Furthermore, the TAK1(Phospho-Ser412) Rabbit Polyclonal Antibody exhibits minimal cross-reactivity with non-phosphorylated TAK1, ensuring specificity and reducing the risk of false-positive results.

The TAK1(Phospho-Ser412) Rabbit Polyclonal Antibody is compatible with a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence. Its versatility allows for seamless integration into various experimental setups, providing researchers with flexibility and convenience. Additionally, this antibody is suitable for use in diverse sample types, including cell lysates, tissue extracts, and cultured cells, further expanding its utility and applicability.

In summary, the TAK1(Phospho-Ser412) Rabbit Polyclonal Antibody is a highly reliable and specific tool for the detection and analysis of phosphorylated TAK1 at Serine 412. With its exceptional sensitivity, accuracy, and compatibility with various applications, this antibody empowers researchers to unravel the complexities of TAK1 signaling pathways and advance their understanding of cellular processes and disease mechanisms.