Tau(Phospho-Ser416) Rabbit Polyclonal Antibody

This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex| regulated alternative splicing| giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system| depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease| Pick's disease| frontotemporal dementia| cortico-basal degeneration and progressive supranuclear palsy.

The Tau(Phospho-Ser416) Rabbit Polyclonal Antibody is a highly specific and sensitive tool for the detection and analysis of Tau protein phosphorylated at Serine 416. This antibody has been rigorously validated and exhibits exceptional performance in various applications, including Western blotting, immunohistochemistry, and immunofluorescence.

The Tau protein plays a crucial role in the assembly and stabilization of microtubules in neurons. Dysregulation of Tau phosphorylation has been implicated in the pathogenesis of neurodegenerative diseases, such as Alzheimer's disease. The phosphorylation of Tau at Serine 416 has been identified as a critical event in the development and progression of these diseases.

This Rabbit Polyclonal Antibody has been meticulously developed using state-of-the-art techniques and high-quality materials to ensure optimal performance and reliability. It exhibits high affinity and specificity towards the phosphorylated form of Tau at Serine 416, enabling accurate and precise detection of this important post-translational modification.

With its exceptional sensitivity, this antibody allows for the detection of even low levels of phosphorylated Tau in complex biological samples. Its versatility enables its use in a wide range of experimental settings, making it an invaluable tool for researchers studying Tau biology and its implications in neurodegenerative diseases.

The Tau(Phospho-Ser416) Rabbit Polyclonal Antibody is supplied in a convenient and user-friendly format, ensuring ease of use and storage. It is provided in a liquid form, ready for immediate use, eliminating the need for time-consuming reconstitution procedures.

In summary, the Tau(Phospho-Ser416) Rabbit Polyclonal Antibody is a highly reliable and efficient tool for the detection and analysis of phosphorylated Tau at Serine 416. Its exceptional sensitivity, specificity, and versatility make it an indispensable asset for researchers in the field of neurodegenerative diseases.