This antibody is specific to a 55 kDa protein known as platelet-derived endothelial growth factor (PD-ECGF), or thymidine phosphorylase (TP). High levels of TP/PD-ECGF are observed in cancer patients. High intracellular levels of TP/PD-ECGF are associated with increased sensitivity to fluoropyrimidine chemotherapeutic agents.
