TLK1(Phospho Ser764) Rabbit Polyclonal Antibody

Catalytic activity:ATP + a protein = ADP + a phosphoprotein.|cofactor:Magnesium.|enzyme regulation:Cell-cycle regulated| maximal activity in S-phase. Inactivated by phosphorylation at Ser-743| potentially by CHK1.|Rapidly and transiently inhibited by phosphorylation following the generation of DNA double-stranded breaks during S-phase. This is cell cycle checkpoint and ATM-pathway dependent and appears to regulate processes involved in chromatin assembly. Isoform 3 phosphorylates and enhances the stability of the t-SNARE SNAP23| augmenting its assembly with syntaxin. Isoform 3 protects the cells from the ionizing radiation by faciliting the repair of DSBs. In vitro| phosphorylates histone H3 at 'Ser-10'.|Belongs to the protein kinase superfamily.|Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.|Contains 1 protein kinase domain.|subunit:Heterodimerizes with TLK2. Interacts with ASF1A and ASF1B.|tissue specificity:Widely expressed. Present in fetal placenta| liver| kidney and pancreas but not heart or skeletal muscle. Also found in adult cell lines. Isoform 3 is ubiquitously expressed in all tissues examined.|

The TLK1(Phospho Ser764) Rabbit Polyclonal Antibody is a highly specific and sensitive tool for the detection and quantification of TLK1 protein phosphorylated at Ser764. This antibody has been rigorously validated for use in various applications, including Western blotting, immunohistochemistry, and immunofluorescence.

The TLK1(Phospho Ser764) Rabbit Polyclonal Antibody exhibits exceptional performance in terms of specificity, sensitivity, and reproducibility. It has been meticulously developed using state-of-the-art techniques and quality control measures to ensure consistent and reliable results.

This antibody is produced from high-quality rabbit polyclonal antibodies that have been affinity-purified to enhance specificity and minimize non-specific binding. It has been extensively tested against a wide range of samples to ensure its suitability for diverse experimental conditions.

The TLK1(Phospho Ser764) Rabbit Polyclonal Antibody is supplied as a liquid formulation in a convenient size, allowing for easy handling and storage. It is provided in a ready-to-use format, eliminating the need for time-consuming and complex preparation steps.

With its exceptional performance and ease of use, the TLK1(Phospho Ser764) Rabbit Polyclonal Antibody is an invaluable tool for researchers studying TLK1 protein phosphorylation. Its high specificity and sensitivity make it ideal for a wide range of applications, enabling accurate and reliable analysis of TLK1 signaling pathways.