TMEM185A Polyclonal Antibody

The protein encoded by TMEM185A (transmembrane protein 185A) is predicted to be a transmembrane protein. TMEM185A is best known for localizing to the CpG island of the fragile site FRAXF. The 5' untranslated region of this gene contains a CGG trinucleotide repeat sequence that normally consists of 7-40 tandem CGG repeats but which can expand to greater than 300 repeats. Methylation of the CpG island leads to transcriptional silencing of this gene, but neither the silencing nor an expanded repeat region appear to manifest itself in a clear phenotypic manner. Alternative splicing results in multiple transcript variants. A pseudogene of TMEM185A has been defined on the X chromosome.

The TMEM185A Polyclonal Antibody is a highly specific and sensitive antibody designed for the detection of TMEM185A protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human TMEM185A protein. The resulting polyclonal antibody has been purified using protein A affinity chromatography and validated for its specificity and sensitivity through various assays, including Western blotting, immunohistochemistry, and immunofluorescence.

The TMEM185A Polyclonal Antibody is suitable for use in a wide range of applications, including research studies on the function and expression of TMEM185A protein in various tissues and cell types. This antibody is also useful for diagnostic purposes, such as the detection of TMEM185A protein in clinical samples for the diagnosis and monitoring of diseases.

The TMEM185A Polyclonal Antibody is provided as a liquid formulation in phosphate-buffered saline (PBS) with 0.02% sodium azide as a preservative. This antibody is available in various sizes to meet the needs of different research and diagnostic applications. With its high specificity and sensitivity, the TMEM185A Polyclonal Antibody is a valuable tool for researchers and clinicians working in the fields of molecular biology, biochemistry, and medicine.