Vangl1 Polyclonal Antibody

VANGL1 encodes a member of the tretraspanin family. The vang-like protein 1 may be involved in mediating intestinal trefoil factor induced wound healing in the intestinal mucosa. Mutations in this gene are associated with neural tube defects. Alternate splicing results in multiple transcript variants.

The Vangl1 Polyclonal Antibody is a highly specific and sensitive antibody designed for the detection of Vangl1 protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human Vangl1 protein. The resulting polyclonal antibody has been purified using protein A affinity chromatography and validated for its specificity and sensitivity through various assays.

The Vangl1 Polyclonal Antibody is suitable for use in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It has been shown to detect endogenous Vangl1 protein in various tissues, including brain, heart, and kidney. This antibody has also been used in studies investigating the role of Vangl1 in various biological processes, such as neural tube closure and planar cell polarity.

This antibody is supplied as a liquid in phosphate-buffered saline (PBS) with 0.02% sodium azide as a preservative. It is recommended to store the antibody at -20°C for long-term storage and to avoid repeated freeze-thaw cycles.

In summary, the Vangl1 Polyclonal Antibody is a reliable and specific tool for the detection of Vangl1 protein in various biological samples. Its high sensitivity and specificity make it an ideal choice for researchers studying the role of Vangl1 in various biological processes.