VASP(Phospho Ser157) Polyclonal Antibody

Vasodilator-stimulated phosphoprotein (VASP) is a member of the Ena-VASP protein family. Ena-VASP family members contain an EHV1 N-terminal domain that binds proteins containing E/DFPPPPXD/E motifs and targets Ena-VASP proteins to focal adhesions. In the mid-region of the protein, family members have a proline-rich domain that binds SH3 and WW domain-containing proteins. Their C-terminal EVH2 domain mediates tetramerization and binds both G and F actin. VASP is associated with filamentous actin formation and likely plays a widespread role in cell adhesion and motility. VASP may also be involved in the intracellular signaling pathways that regulate integrin-extracellular matrix interactions. VASP is regulated by the cyclic nucleotide-dependent kinases PKA and PKG.

The VASP(PHOSPHO SER157) Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of VASP protein phosphorylated at serine 157. This antibody is produced using advanced polyclonal antibody production techniques, ensuring high affinity and specificity towards the target epitope.

The VASP(PHOSPHO SER157) Polyclonal Antibody exhibits exceptional sensitivity and selectivity, making it an ideal choice for various applications, including Western blotting, immunohistochemistry, and immunofluorescence. Its superior performance allows for accurate and precise quantification of VASP phosphorylation at serine 157, enabling researchers to gain valuable insights into cellular signaling pathways and protein regulation.

This antibody is meticulously validated to ensure consistent and reproducible results. It has been extensively tested against a wide range of samples, including human, mouse, and rat tissues, guaranteeing its broad applicability across different species. Furthermore, the VASP(PHOSPHO SER157) Polyclonal Antibody demonstrates excellent stability and long shelf life, ensuring reliable performance throughout its usage.

With its exceptional quality and reliability, the VASP(PHOSPHO SER157) Polyclonal Antibody is an indispensable tool for researchers in the fields of cell biology, molecular biology, and biochemistry. It provides a valuable means to investigate the role of VASP phosphorylation at serine 157 in various physiological and pathological processes, ultimately contributing to the advancement of scientific knowledge and understanding.