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ELK Biotechnology
SKU(재고 관리 코드):ES10454
VATB2 Rabbit Polyclonal Antibody
VATB2 Rabbit Polyclonal Antibody
VATB2 Rabbit Polyclonal Antibody
Overview
| Product name: | VATB2 rabbit pAb |
| Applications: | WB;ELISA |
| Recommended Dilutions: | WB 1:500-2000 ELISA 1:5000-20000 |
| Immunogen: | Synthesized peptide derived from part region of human protein |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 56kD |
| GeneID（Human）: | 526 |
| Human Swiss-Prot No: | P21281 |
| Cellular localization: | Apical cell membrane . Melanosome . Cytoplasm . Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane ; Peripheral membrane protein . Cytoplasmic vesicle, clathrin-coated vesicle membrane ; Peripheral membrane protein . Identified by mass spectrometry in melanosome fractions from stage I to stage IV. . |
| Background: | This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A, three B, and two G subunits, as well as a C, D, E, F, and H subunit. The V1 domain contains the ATP catalytic site. The protein encoded by this gene is one of two V1 domain B subunit isoforms and is the only B isoform highly expressed in osteoclasts. [provided by RefSeq, Jul 2008], |
| Species Reactivity: | Human;Rat;Mouse;Swine |
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