WNK3 Polyclonal Antibody

This gene encodes a protein belonging to the 'with no lysine' family of serine-threonine protein kinases. These family members lack the catalytic lysine in subdomain II, and instead have a conserved lysine in subdomain I. This family member functions as a positive regulator of the transcellular Ca2+ transport pathway, and it plays a role in the increase of cell survival in a caspase-3-dependent pathway. Alternative splicing results in multiple transcript variants.

The WNK3 Polyclonal Antibody is a highly specific and sensitive immunological reagent designed for the detection and quantification of WNK3 protein expression in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human WNK3 protein. The resulting polyclonal antibody exhibits high affinity and specificity towards WNK3 protein, making it an ideal tool for various applications such as Western blotting, immunohistochemistry, and immunofluorescence.

The WNK3 Polyclonal Antibody is validated for use in human, mouse, and rat samples, and has been extensively tested for its specificity and sensitivity. It is capable of detecting endogenous levels of WNK3 protein in various tissues and cell lines, and can be used to study the expression and localization of WNK3 protein in different physiological and pathological conditions.

This antibody is supplied as a purified IgG fraction, and is available in different sizes and formats to suit various experimental needs. It is recommended to use this antibody at a dilution of 1:1000 for Western blotting, and at a dilution of 1:200 for immunohistochemistry and immunofluorescence. The WNK3 Polyclonal Antibody is a reliable and high-quality reagent that can help researchers to advance their understanding of the role of WNK3 protein in various biological processes.