WRN Rabbit Polyclonal Antibody

This gene encodes a member of the RecQ subfamily and the DEAH (Asp-Glu-Ala-His) subfamily of DNA and RNA helicases. DNA helicases are involved in many aspects of DNA metabolism| including transcription| replication| recombination| and repair. This protein contains a nuclear localization signal in the C-terminus and shows a predominant nucleolar localization. It possesses an intrinsic 3' to 5' DNA helicase activity| and is also a 3' to 5' exonuclease. Based on interactions between this protein and Ku70/80 heterodimer in DNA end processing| this protein may be involved in the repair of double strand DNA breaks. Defects in this gene are the cause of Werner syndrome| an autosomal recessive disorder characterized by premature aging.

The WRN Rabbit Polyclonal Antibody is a highly specific and reliable tool for the detection and analysis of Werner syndrome protein (WRN) in various biological samples. This antibody has been meticulously developed and rigorously tested to ensure optimal performance and accuracy in research applications.

The WRN Rabbit Polyclonal Antibody exhibits exceptional sensitivity and specificity, making it an ideal choice for immunohistochemistry (IHC), immunofluorescence (IF), and western blotting (WB) experiments. It recognizes the WRN protein with high affinity, enabling precise and efficient detection of this crucial protein in both normal and disease states.

This antibody is produced using state-of-the-art techniques, ensuring batch-to-batch consistency and reliability. It has been validated for use in a wide range of species, including human, mouse, and rat, making it versatile and suitable for various experimental models.

The WRN Rabbit Polyclonal Antibody is supplied as a liquid formulation, allowing for easy and convenient handling. It is provided in a ready-to-use format, eliminating the need for time-consuming and complex preparation steps. The antibody is also available in different sizes to accommodate various experimental needs.

With its exceptional performance and reliability, the WRN Rabbit Polyclonal Antibody is an indispensable tool for researchers studying the role of WRN protein in aging, DNA repair, and various age-related diseases. Its high specificity and sensitivity make it an invaluable asset in elucidating the molecular mechanisms underlying Werner syndrome and related disorders.

Choose the WRN Rabbit Polyclonal Antibody for accurate and reproducible results in your research endeavors.