XPG Polyclonal Antibody

ERCC5 encodes a single-strand specific DNA endonuclease that makes the 3' incision in DNA excision repair following UV-induced damage. DNA repair protein complementing XP-G cells may also function in other cellular processes, including RNA polymerase II transcription, and transcription-coupled DNA repair. Mutations in this gene cause xeroderma pigmentosum complementation group G (XP-G), which is also referred to as xeroderma pigmentosum VII (XP7), a skin disorder characterized by hypersensitivity to UV light and increased susceptibility for skin cancer development following UV exposure. Some patients also develop Cockayne syndrome, which is characterized by severe growth defects, mental retardation, and cachexia. Read-through transcription exists between this gene and the neighboring upstream BIVM (basic, immunoglobulin-like variable motif containing) gene.

The XPG Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of XPG protein expression in various biological samples. This antibody is produced using advanced immunization techniques, ensuring high affinity and sensitivity towards the target protein.

The XPG Polyclonal Antibody exhibits exceptional performance in a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence. Its superior specificity enables accurate identification and quantification of XPG protein levels, facilitating comprehensive research in the field of DNA repair and genome stability.

With its robust and consistent performance, this antibody guarantees reproducible results, making it an ideal choice for both routine laboratory experiments and cutting-edge scientific investigations. Its versatility allows for seamless integration into various experimental protocols, providing researchers with the flexibility to explore diverse research avenues.

The XPG Polyclonal Antibody is manufactured under stringent quality control measures, ensuring batch-to-batch consistency and reliability. Each lot is thoroughly tested to meet the highest standards of quality, purity, and specificity. This commitment to excellence ensures that researchers can rely on this antibody for accurate and reproducible results, ultimately advancing scientific knowledge and discovery.

In summary, the XPG Polyclonal Antibody is a highly specific, reliable, and versatile tool that enables precise detection and analysis of XPG protein expression. With its exceptional performance and stringent quality control, this antibody is an indispensable asset for researchers in the field of DNA repair and genome stability.