XRCC1 Polyclonal Antibody

DNA repair protein XRCC1 encoded by XRCC1 is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.

The XRCC1 Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of XRCC1 protein expression in various biological samples. This antibody is produced using advanced immunization techniques, ensuring high affinity and specificity towards XRCC1.

XRCC1, also known as X-ray repair cross-complementing protein 1, plays a crucial role in the repair of DNA damage caused by ionizing radiation and other genotoxic agents. It acts as a scaffold protein, facilitating the assembly of DNA repair complexes and promoting efficient DNA repair processes.

The XRCC1 Polyclonal Antibody has been extensively validated for its performance in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It exhibits excellent sensitivity and specificity, enabling accurate and reliable detection of XRCC1 protein expression in a wide range of sample types, such as cell lysates, tissue sections, and whole-cell extracts.

This antibody is supplied as a liquid formulation, ready to use for immediate application. It is provided in a convenient size, ensuring cost-effective usage without compromising on quality. The XRCC1 Polyclonal Antibody is manufactured under strict quality control standards, guaranteeing consistent and reproducible results.

In summary, the XRCC1 Polyclonal Antibody is a valuable tool for researchers and scientists involved in DNA repair studies, genotoxicity research, and related fields. Its high specificity, sensitivity, and reliability make it an indispensable asset for investigating the role of XRCC1 in DNA repair mechanisms and its potential implications in various diseases, including cancer.