XRCC3 Polyclonal Antibody

XRCC3 encodes a member of the RecA/Rad51-related protein family that participates in homologous recombination to maintain chromosome stability and repair DNA damage. This gene functionally complements Chinese hamster irs1SF, a repair-deficient mutant that exhibits hypersensitivity to a number of different DNA-damaging agents and is chromosomally unstable. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. Alternatively spliced transcript variants encoding the same protein have been identified.

The XRCC3 Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of XRCC3 protein expression in various biological samples. This antibody is produced using advanced immunization techniques, ensuring high affinity and specificity towards XRCC3.

XRCC3, also known as X-ray repair cross-complementing protein 3, plays a crucial role in DNA repair and maintenance of genomic stability. It is involved in the homologous recombination repair pathway, which is essential for repairing DNA double-strand breaks. Dysregulation or mutations in XRCC3 have been associated with increased susceptibility to cancer and other genetic disorders.

The XRCC3 Polyclonal Antibody has been extensively validated for its performance in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It exhibits excellent sensitivity and specificity, enabling accurate and reliable detection of XRCC3 protein expression in both normal and disease states.

This antibody is supplied as a liquid formulation, ready for immediate use. It is provided in a convenient size and concentration, ensuring cost-effectiveness and minimizing wastage. The XRCC3 Polyclonal Antibody is compatible with a wide range of sample types, including cell lysates, tissue extracts, and purified proteins.

With its exceptional performance and versatility, the XRCC3 Polyclonal Antibody is an indispensable tool for researchers and scientists studying DNA repair mechanisms, genomic stability, and related fields. Its reliable and reproducible results make it an ideal choice for both basic research and clinical applications.

Order your XRCC3 Polyclonal Antibody today and unlock new insights into the intricate world of DNA repair and maintenance.