• DNA pol β (Acetyl Lys72) rabbit pAb
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Upingbio

YP-Ab-00919-100UL

DNA pol β (Acetyl Lys72) rabbit pAb

DNA pol β (Acetyl Lys72) rabbit pAb

Size
  • Gene Name: POLB
  • Immunogen: Synthesized peptide derived from human DNA pol β (Acetyl Lys72)
  • Specificity: This antibody detects endogenous levels of Human,Mouse,Rat DNA pol β (Acetyl Lys72)
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: WB 1:1000-2000 ELISA 1:5000-20000
  • Purification process: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Other Names: DNA polymerase beta (EC 2.7.7.7;EC 4.2.99.-)
  • Background: catalytic activity:Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).,cofactor:Binds 2 magnesium ions per subunit.,domain:Residues 239-252 form a flexible loop which appears to affect the polymerase fidelity.,function:Repair polymerase. Conducts "gap-filling" DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases. Has a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.,PTM:Methylation by PRMT6 stimulates the polymerase activity by enhancing DNA binding and processivity.,similarity:Belongs to the DNA polymerase type-X family.,subunit:Monomer.,
  • Function: DNA metabolic process, DNA replication, DNA-dependent DNA replication, DNA repair, base-excision repair, pyrimidine dimer repair, anti-apoptosis, response to DNA damage stimulus, cell death, regulation of cell death, death, cellular response to stress, regulation of apoptosis, negative regulation of apoptosis, regulation of programmed cell death,negative regulation of programmed cell death, negative regulation of cell death,
  • Species: Human;Mouse;Rat
  • Range: WB; ELISA
  • Protein: DNA pol β (Acetyl Lys72)
  • DA: 38kD
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