• FOXP3 Polyclonal Antibody
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YP-Ab-02246-100UL

FOXP3 Polyclonal Antibody

FOXP3 Polyclonal Antibody

Size
  • Gene Name: FOXP3
  • Immunogen: The antiserum was produced against synthesized peptide derived from the C-terminal region of human FOXP3. AA range:381-430
  • Specificity: FOXP3 Polyclonal Antibody detects endogenous levels of FOXP3 protein.
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: WB: 1/500 - 1/2000. IHC-p: 1/100-1/300. ELISA: 1/20000.. IF 1:50-200
  • Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Other Names: FOXP3; IPEX; JM2; Forkhead box protein P3; Scurfin
  • Background: The protein encoded by this gene is a member of the forkhead/winged-helix family of transcriptional regulators. Defects in this gene are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX), also known as X-linked autoimmunity-immunodeficiency syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008],
  • Function: disease:Defects in FOXP3 are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) [MIM:304790]; also known as X-linked autoimmunity-immunodeficiency syndrome. IPEX is characterized by neonatal onset insulin-dependent diabetes mellitus, infections, secretory diarrhea, trombocytopenia, anemia and eczema. It is usually lethal in infancy.,function:Probable transcription factor. Plays a critical role in the control of immune response.,online information:FOXP3 entry,online information:FOXP3 mutation db,similarity:Contains 1 C2H2-type zinc finger.,similarity:Contains 1 fork-head DNA-binding domain.,
  • Species: Human;Mouse;Rat;Pig
  • Range: WB;IHC;IF;ELISA
  • Protein: Forkhead box protein P3
  • DA: 47kD
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