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Upingbio
SKU(재고 관리 코드):YP-Ab-02891-100UL
TIMP-4 Polyclonal Antibody
TIMP-4 Polyclonal Antibody
- Gene Name: TIMP4
- Immunogen: Synthesized peptide derived from TIMP-4 at AA range: 174-223
- Specificity: TIMP-4 Polyclonal Antibody detects endogenous levels of TIMP-4
- Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source: Polyclonal, Rabbit,IgG
- Dilution ratio: WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
- Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration: 1 mg/ml
- Storage: -20°C/1 year
- Other Names: Metalloproteinase inhibitor 4 (Tissue inhibitor of metalloproteinases 4) (TIMP-4)
- Background: This gene belongs to the TIMP gene family. The proteins encoded by this gene family are inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. The secreted, netrin domain-containing protein encoded by this gene is involved in regulation of platelet aggregation and recruitment and may play role in hormonal regulation and endometrial tissue remodeling. [provided by RefSeq, Jul 2008],
- Function: function:Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them. Known to act on MMP-1, MMP-2, MMP-3, MMP-7 and MMP-9.,similarity:Belongs to the protease inhibitor I35 (TIMP) family.,similarity:Contains 1 NTR domain.,tissue specificity:Abundant in heart and present at low levels in many other tissues.,
- Species: Human;Rat;Mouse;
- Range: WB;ELISA;IHC
- Protein: TIMP-4
- DA: 26kD
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