1
/
의
1
Upingbio
SKU(재고 관리 코드):YP-Ab-03891-100UL
GCKR Polyclonal Antibody
GCKR Polyclonal Antibody
- Gene Name: GCKR
- Immunogen: The antiserum was produced against synthesized peptide derived from human Glucokinase Regulator. AA range:211-260
- Specificity: GCKR Polyclonal Antibody detects endogenous levels of GCKR protein.
- Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source: Polyclonal, Rabbit,IgG
- Dilution ratio: Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
- Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration: 1 mg/ml
- Storage: -20°C/1 year
- Other Names: GCKR; Glucokinase regulatory protein; Glucokinase regulator
- Background: This gene encodes a protein belonging to the GCKR subfamily of the SIS (Sugar ISomerase) family of proteins. The gene product is a regulatory protein that inhibits glucokinase in liver and pancreatic islet cells by binding non-covalently to form an inactive complex with the enzyme. This gene is considered a susceptibility gene candidate for a form of maturity-onset diabetes of the young (MODY). [provided by RefSeq, Jul 2008],
- Function: function:Inhibits glucokinase by forming an inactive complex with this enzyme.,similarity:Belongs to the GCKR family.,similarity:Contains 1 SIS domain.,tissue specificity:Found in liver and pancreas. Not detected in muscle, brain, heart, thymus, intestine, uterus, adipose tissue, kidney, adrenal, lung or spleen.,
- Species: Human;Mouse;Rat
- Range: WB;ELISA
- Protein: Glucokinase regulatory protein
- DA: 68kD
Share
