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Upingbio
SKU(재고 관리 코드):YP-Ab-04200-100UL
Septin 6 Polyclonal Antibody
Septin 6 Polyclonal Antibody
- Gene Name: 45175
- Immunogen: The antiserum was produced against synthesized peptide derived from human SEPT6. AA range:223-272
- Specificity: Septin 6 Polyclonal Antibody detects endogenous levels of Septin 6 protein.
- Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source: Polyclonal, Rabbit,IgG
- Dilution ratio: WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/40000.. IF 1:50-200
- Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration: 1 mg/ml
- Storage: -20°C/1 year
- Other Names: SEPT6; KIAA0128; SEP2; Septin-6
- Background: septin 6(SEPT6) Homo sapiens This gene is a member of the septin family of GTPases. Members of this family are required for cytokinesis. One version of pediatric acute myeloid leukemia is the result of a reciprocal translocation between chromosomes 11 and X, with the breakpoint associated with the genes encoding the mixed-lineage leukemia and septin 2 proteins. This gene encodes four transcript variants encoding three distinct isoforms. An additional transcript variant has been identified, but its biological validity has not been determined. [provided by RefSeq, Jul 2008],
- Function: function:Involved in cytokinesis .,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the septin family.,subunit:Heterohexamer composed of two heterotrimers containing one copy each of SEPT2, SEPT6 and SEPT7. The asymmetrical heterotrimers associate head-to-head to form a hexameric unit that assembles into filaments. Interacts with SEPT12. Interaction with SEPT12 alters filament structure.,
- Species: Human;Mouse;Rat
- Range: WB;IHC;IF;ELISA
- Protein: Septin-6
- DA: 50kD
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