1
/
의
1
Upingbio
SKU(재고 관리 코드):YP-Ab-05076-100UL
FRAT1 Polyclonal Antibody
FRAT1 Polyclonal Antibody
- Gene Name: FRAT1
- Immunogen: Synthesized peptide derived from human protein . at AA range: 130-210
- Specificity: FRAT1 Polyclonal Antibody detects endogenous levels of protein.
- Composition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
- Source: Polyclonal, Rabbit,IgG
- Dilution ratio: WB 1:500-2000 ELISA 1:5000-20000
- Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration: 1 mg/ml
- Storage: -20°C/1 year
- Background: The protein encoded by this gene belongs to the GSK-3-binding protein family. The protein inhibits GSK-3-mediated phosphorylation of beta-catenin and positively regulates the Wnt signaling pathway. It may function in tumor progression and in lymphomagenesis. [provided by RefSeq, Oct 2008],
- Function: function:Positively regulates the Wnt signaling pathway by stabilizing beta-catenin through the association with GSK-3. May play a role in tumor progression and collaborate with PIM1 and MYC in lymphomagenesis.,PTM:Phosphorylated.,similarity:Belongs to the GSK-3-binding protein family.,subunit:Binds DVL1. Binds GSK-3 and prevent GSK-3-dependent phosphorylation.,
- Species: Human;Mouse
- Range: WB;ELISA
- Protein: Proto-oncogene FRAT1 (Frequently rearranged in advanced T-cell lymphomas 1) (FRAT-1)
- DA: 30kD
Share
