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Upingbio
SKU(재고 관리 코드):YP-Ab-06034-100UL
RAC3 Polyclonal Antibody
RAC3 Polyclonal Antibody
- Gene Name: RAC3
- Immunogen: Synthesized peptide derived from human protein . at AA range: 80-160
- Specificity: RAC3 Polyclonal Antibody detects endogenous levels of protein.
- Composition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
- Source: Polyclonal, Rabbit,IgG
- Dilution ratio: WB 1:500-2000 ELISA 1:5000-20000
- Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration: 1 mg/ml
- Storage: -20°C/1 year
- Background: The protein encoded by this gene is a GTPase which belongs to the RAS superfamily of small GTP-binding proteins. Members of this superfamily appear to regulate a diverse array of cellular events, including the control of cell growth, cytoskeletal reorganization, and the activation of protein kinases. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015],
- Function: function:Plasma membrane-associated small GTPase which cycles between an active GTP-bound and inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses, such as cell spreading and the formation of actin-based protusions including lamellipodia and membrane ruffles.,induction:Expression down-regulated in quiescent fibroblasts and clearly induced by serum stimulation.,similarity:Belongs to the small GTPase superfamily. Rho family.,subcellular location:Membrane-associated when activated. Co-localizes with NRBP to endomembranes and at the cell periphery in lamellipodia.,subunit:Interacts with the GEF protein DOCK7, which promotes the exchange between GDP and GTP, and therefore activates it. Interacts with C1D.,tissue specificity:Highest levels in brain, also detected in heart, placenta and pancreas.,
- Species: Human;Mouse
- Range: WB;ELISA
- Protein: Ras-related C3 botulinum toxin substrate 3 (p21-Rac3)
- DA: 21kD
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