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Upingbio
SKU(재고 관리 코드):YP-Ab-06617-100UL
HS74L Polyclonal Antibody
HS74L Polyclonal Antibody
- Gene Name: HSPA4L APG1 OSP94
- Immunogen: Synthesized peptide derived from human protein . at AA range: 450-530
- Specificity: HS74L Polyclonal Antibody detects endogenous levels of protein.
- Composition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
- Source: Polyclonal, Rabbit,IgG
- Dilution ratio: WB 1:500-2000 ELISA 1:5000-20000
- Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration: 1 mg/ml
- Storage: -20°C/1 year
- Background: The protein encoded by this gene is heat shock inducible and may act as a chaperone. The encoded protein can protect the heat-shocked cell against the harmful effects of aggregated proteins. This gene is highly expressed in leukemia cells and may be a good target for therapeutic intervention. Several transcripts encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2015],
- Function: function:Possesses chaperone activity in vitro where it inhibits aggregation of citrate synthase.,induction:By heat shock.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the heat shock protein 70 family.,subcellular location:May translocate to the nucleus after heat shock.,subunit:Homodimer.,
- Species: Human;Mouse
- Range: WB;ELISA
- Protein: Heat shock 70 kDa protein 4L (Heat shock 70-related protein APG-1) (Osmotic stress protein 94)
- DA: 92kD
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