• REV1 Polyclonal Antibody
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YP-Ab-06675-100UL

REV1 Polyclonal Antibody

REV1 Polyclonal Antibody

Size
  • Gene Name: REV1 REV1L
  • Immunogen: Synthesized peptide derived from part region of human protein
  • Specificity: REV1 Polyclonal Antibody detects endogenous levels of protein.
  • Composition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: WB 1:500-2000 ELISA 1:5000-20000
  • Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Background: This gene encodes a protein with similarity to the S. cerevisiae mutagenesis protein Rev1. The Rev1 proteins contain a BRCT domain, which is important in protein-protein interactions. A suggested role for the human Rev1-like protein is as a scaffold that recruits DNA polymerases involved in translesion synthesis (TLS) of damaged DNA. [provided by RefSeq, Mar 2016],
  • Function: domain:The C-terminal domain is necessary for protein interactions.,function:Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template-dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents.,similarity:Belongs to the DNA polymerase type-Y family.,similarity:Contains 1 BRCT domain.,similarity:Contains 1 umuC domain.,subunit:Monomer. Binds MAD2L2, POLH, POLI, POLK and REV3L. May bind ITGA3.,tissue specificity:Ubiquitous.,
  • Species: Human;Rat;Mouse;
  • Range: WB;ELISA
  • Protein: DNA repair protein REV1 (EC 2.7.7.-) (Alpha integrin-binding protein 80) (AIBP80) (Rev1-like terminal deoxycytidyl transferase)
  • DA: 137kD
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