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Upingbio
SKU(재고 관리 코드):YP-Ab-06790-100UL
UVRAG Polyclonal Antibody
UVRAG Polyclonal Antibody
- Gene Name: UVRAG
- Immunogen: Synthesized peptide derived from part region of human protein. AA range 655-675
- Specificity: UVRAG Polyclonal Antibody detects endogenous levels of protein.
- Composition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
- Source: Polyclonal, Rabbit,IgG
- Dilution ratio: WB 1:500-2000 ELISA 1:5000-20000
- Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration: 1 mg/ml
- Storage: -20°C/1 year
- Background: This gene complements the ultraviolet sensitivity of xeroderma pigmentosum group C cells and encodes a protein with a C2 domain. The protein activates the Beclin1-PI(3)KC3 complex, promoting autophagy and suppressing the proliferation and tumorigenicity of human colon cancer cells. Chromosomal aberrations involving this gene are associated with left-right axis malformation and mutations in this gene have been associated with colon cancer. [provided by RefSeq, Jul 2008],
- Function: disease:Disrupted by a Inv(11)(q13.5;q25) inversion in a patient with heterotaxy (left-right axis malformation).,similarity:Contains 1 C2 domain.,tissue specificity:Highly expressed in brain, lung, kidney and liver.,
- Species: Human;Rat;Mouse;
- Range: WB;ELISA
- Protein: UV radiation resistance-associated gene protein (p63)
- DA: 76kD
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