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Upingbio
SKU(재고 관리 코드):YP-Ab-07037-100UL
PORIM Polyclonal Antibody
PORIM Polyclonal Antibody
- Gene Name: TMEM123 KCT3 PSEC0111 UNQ641/PRO1271
- Immunogen: Synthesized peptide derived from part region of human protein
- Specificity: PORIM Polyclonal Antibody detects endogenous levels of protein.
- Composition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
- Source: Polyclonal, Rabbit,IgG
- Dilution ratio: WB 1:500-2000 ELISA 1:5000-20000
- Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration: 1 mg/ml
- Storage: -20°C/1 year
- Background: This gene encodes a highly glycosylated transmembrane protein with a high content of threonine and serine residues in its extracellular domain, similar to a broadly defined category of proteins termed mucins. Exposure of some cell types to anti-PORIMIN (pro-oncosis receptor inducing membrane injury) antibody, crosslinks this protein on the cell surface and induces a type of cell death termed oncosis. Oncosis is distinct from apoptosis and is characterized by a loss of cell membrane integrity without DNA fragmentation. This gene product is proposed to function as a cell surface receptor that mediates cell death. [provided by RefSeq, Jul 2008],
- Function: function:Implicated in oncotic cell death, characterized by cell swelling, organelle swelling, vacuolization and increased membrane permeability.,similarity:Belongs to the CD164 family.,tissue specificity:Ubiquitous. Not expressed in ovary. Expressed in keratinocytes.,
- Species: Human;Rat;Mouse
- Range: WB;ELISA
- Protein: Porimin (Keratinocytes-associated transmembrane protein 3) (KCT-3) (Pro-oncosis receptor inducing membrane injury) (Transmembrane protein 123)
- DA: 22kD
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