• C5ARL Polyclonal Antibody
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YP-Ab-07387-100UL

C5ARL Polyclonal Antibody

C5ARL Polyclonal Antibody

Size
  • Gene Name: GPR77 C5L2
  • Immunogen: Synthesized peptide derived from human protein . at AA range: 270-350
  • Specificity: C5ARL Polyclonal Antibody detects endogenous levels of protein.
  • Composition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: WB 1:500-2000 ELISA 1:5000-20000
  • Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Background: This gene encodes a G-protein coupled receptor 1 family member involved in the complement system of the innate immune response. Unlike classical G-protein coupled receptors, the encoded protein does not associate with intracellular G-proteins. It may instead modulate signal transduction through the beta-arrestin pathway, and may alternatively act as a decoy receptor. This gene may be involved in coronary artery disease and in the pathogenesis of sepsis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2012],
  • Function: function:Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a, C4a and C3a and their desarginated derivatives. Couples weakly to Gi-mediated signaling pathways.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Frontal cortex, hippocampus, hypothalamus, pons and liver.,
  • Species: Human;Rat;Mouse;
  • Range: WB;ELISA
  • Protein: C5a anaphylatoxin chemotactic receptor C5L2 (G-protein coupled receptor 77)
  • DA: 37kD
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