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Upingbio
SKU(재고 관리 코드):YP-Ab-08162-100UL
SNX13 rabbit pAb
SNX13 rabbit pAb
- Gene Name: SNX13 KIAA0713
- Immunogen: Synthesized peptide derived from human SNX13 AA range: 602-652
- Specificity: This antibody detects endogenous levels of SNX13 at Human/Mouse
- Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.277% sodium azide.
- Source: Polyclonal, Rabbit,IgG
- Dilution ratio: WB 1:500-2000
- Purification process: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
- Concentration: 1 mg/ml
- Storage: -20°C/1 year
- Other Names: Sorting nexin-13 (RGS domain- and PHOX domain-containing protein) (RGS-PX1)
- Background: This gene encodes a PHOX domain- and RGS domain-containing protein that belongs to the sorting nexin (SNX) family and the regulator of G protein signaling (RGS) family. The PHOX domain is a phosphoinositide binding domain, and the SNX family members are involved in intracellular trafficking. The RGS family members are regulatory molecules that act as GTPase activating proteins for G alpha subunits of heterotrimeric G proteins. The RGS domain of this protein interacts with G alpha(s), accelerates its GTP hydrolysis, and attenuates G alpha(s)-mediated signaling. Overexpression of this protein delayes lysosomal degradation of the epidermal growth factor receptor. Because of its bifunctional role, this protein may link heterotrimeric G protein signaling and vesicular trafficking. [provided by RefSeq, Jul 2008],
- Function: function:May be involved in several stages of intracellular trafficking. Act as a GAP for Galphas.,similarity:Belongs to the sorting nexin family.,similarity:Contains 1 PX (phox homology) domain.,similarity:Contains 1 PXA domain.,similarity:Contains 1 RGS domain.,
- Species: Human; Mouse
- Range: WB
- Protein: SNX13
- DA: 105kD
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