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Upingbio
SKU(재고 관리 코드):YP-Ab-08238-100UL
YMEL1 rabbit pAb
YMEL1 rabbit pAb
- Gene Name: YME1L1 FTSH1 YME1L UNQ1868/PRO4304
- Immunogen: Synthesized peptide derived from human YMEL1 AA range: 136-186
- Specificity: This antibody detects endogenous levels of YMEL1 at Human/Mouse/Rat
- Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.353% sodium azide.
- Source: Polyclonal, Rabbit,IgG
- Dilution ratio: WB 1:500-2000
- Purification process: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
- Concentration: 1 mg/ml
- Storage: -20°C/1 year
- Other Names: ATP-dependent zinc metalloprotease YME1L1 (EC 3.4.24.-) (ATP-dependent metalloprotease FtsH1) (Meg-4) (Presenilin-associated metalloprotease) (PAMP) (YME1-like protein 1)
- Background: The protein encoded by this gene is the human ortholog of yeast mitochondrial AAA metalloprotease, Yme1p. It is localized in the mitochondria and can functionally complement a yme1 disruptant yeast strain. It is proposed that this gene plays a role in mitochondrial protein metabolism and could be involved in mitochondrial pathologies. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011],
- Function: cofactor:Binds 1 zinc ion per subunit .,function:Putative ATP-dependent protease which plays a role in mitochondrial protein metabolism.,similarity:In the C-terminal section; belongs to the peptidase M41 family.,similarity:In the N-terminal section; belongs to the AAA ATPase family.,
- Species: Human; Mouse;Rat
- Range: WB
- Protein: YMEL1
- DA: 85kD
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