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Upingbio
SKU(재고 관리 코드):YP-Ab-08388-100UL
NUDT5 rabbit pAb
NUDT5 rabbit pAb
- Gene Name: NUDT5 HSPC115
- Immunogen: Synthesized peptide derived from human NUDT5 AA range: 95-145
- Specificity: This antibody detects endogenous levels of NUDT5 at Human/Mouse/Rat
- Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source: Polyclonal, Rabbit,IgG
- Dilution ratio: WB 1：500-2000
- Purification process: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
- Concentration: 1 mg/ml
- Storage: -20°C/1 year
- Background: This gene belongs to the Nudix (nucleoside diphosphate linked moiety X) hydrolase superfamily. The encoded enzyme catalyzes the hydrolysis of modified nucleoside diphosphates, including ADP-ribose (ADPR) and 8-oxoGua-containing 8-oxo-dADP and 8-oxo-dGDP. Protein-bound ADP ribose can be hazardous to the cell because it can modify some amino acid residues, resulting in the inhibition of ATP-activated potassium channels. 8-oxoGua is an oxidized form of guanine that can potentially alter genetic information by pairing with adenine and cytosine in RNA. Presence of 8-oxoGua in RNA results in formation of abnormal proteins due to translational errors. [provided by RefSeq, Aug 2013],
- Function: catalytic activity:ADP-ribose + H(2)O = AMP + D-ribose 5-phosphate.,catalytic activity:ADP-sugar + H(2)O = AMP + alpha-D-aldose 5-phosphate.,cofactor:Magnesium.,function:Hydrolyzes with similar activities ADP-ribose, ADP-mannose, and ADP-glucose. Can also hydrolyze other nucleotide sugars with low activity.,similarity:Belongs to the Nudix hydrolase family.,subunit:Homodimer.,tissue specificity:Widely expressed. Most abundant in liver.,
- Species: Human; Mouse;Rat
- Range: WB
- Protein: NUDT5
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