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Upingbio
SKU(재고 관리 코드):YP-Ab-09085-100UL
SHRM3 rabbit pAb
SHRM3 rabbit pAb
- Gene Name: SHROOM3 KIAA1481 SHRML MSTP013
- Immunogen: Synthesized peptide derived from human SHRM3 AA range: 777-827
- Specificity: This antibody detects endogenous levels of SHRM3 at Human/Mouse
- Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source: Polyclonal, Rabbit,IgG
- Dilution ratio: WB 1：500-2000
- Purification process: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
- Concentration: 1 mg/ml
- Storage: -20°C/1 year
- Background: This gene encodes a PDZ-domain-containing protein that belongs to a family of Shroom-related proteins. This protein may be involved in regulating cell shape in certain tissues. A similar protein in mice is required for proper neurulation. [provided by RefSeq, Jan 2011],
- Function: domain:The ASD1 domain mediates F-actin binding.,domain:The ASD2 domain is required for apical constriction induction.,function:Controls cell shape changes in the neuroepithelium during neural tube closure. Induces apical constriction in epithelial cells by promoting the apical accumulation of F-actin and myosin II, and probably by bundling stress fibers. Induces apicobasal cell elongation by redistributing gamma-tubulin and directing the assembly of robust apicobasal microtubule arrays.,similarity:Belongs to the shroom family.,similarity:Contains 1 ASD1 domain.,similarity:Contains 1 ASD2 domain.,similarity:Contains 1 PDZ (DHR) domain.,subcellular location:Colocalizes with F-actin in stress fibers and adherens junctions.,subunit:Interacts with F-actin.,
- Species: Human; Mouse
- Range: WB
- Protein: SHRM3
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