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Upingbio
SKU(재고 관리 코드):YP-Ab-10580-100UL
SSTR2 Polyclonal Antibody
SSTR2 Polyclonal Antibody
- Gene Name: SSTR2
- Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human SSTR2. AA range:220-270
- Specificity: SSTR2 Polyclonal Antibody detects endogenous levels of somatostatin receptor 2
- Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source: Polyclonal, Rabbit,IgG
- Dilution ratio: Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
- Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration: 1 mg/ml
- Storage: -20°C/1 year
- Other Names: Somatostatin receptor type 2 (SS-2-R) (SS2-R) (SS2R) (SRIF-1)
- Background: Somatostatin acts at many sites to inhibit the release of many hormones and other secretory proteins. The biologic effects of somatostatin are probably mediated by a family of G protein-coupled receptors that are expressed in a tissue-specific manner. SSTR2 is a member of the superfamily of receptors having seven transmembrane segments and is expressed in highest levels in cerebrum and kidney. [provided by RefSeq, Jul 2008],
- Function: function:Receptor for somatostatins-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and PLC via pertussis toxin insensitive as well as sensitive G proteins. In RIN-5F cells, this receptor inhibits calcium entry by suppressing voltage dependent calcium-channels.,similarity:Belongs to the G-protein coupled receptor 1 family.,subunit:The C-terminus interacts with SHANK1 PDZ domain.,tissue specificity:Cerebrum and kidney. In lesser amounts in jejunum, colon and liver.,
- Species: Human;Mouse;Rat
- Range: WB;ELISA
- Protein: somatostatin receptor 2
- DA: 40kD
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