• NALP4 rabbit pAb
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YP-Ab-11590-100UL

NALP4 rabbit pAb

NALP4 rabbit pAb

Size
  • Gene Name: NLRP4 NALP4 PAN2 PYPAF4 RNH2
  • Immunogen: Synthesized peptide derived from human NALP4 AA range: 307-357
  • Specificity: This antibody detects endogenous levels of NALP4 at Human
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: WB 1:500-2000;IHC-p 1:50-300
  • Purification process: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Background: NALPs are cytoplasmic proteins that form a subfamily within the larger CATERPILLER protein family. Most short NALPs, such as NALP4, have an N-terminal pyrin (MEFV; MIM 608107) domain (PYD), followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. The long NALP, NALP1 (MIM 606636), also has a C-terminal extension containing a function to find domain (FIIND) and a caspase recruitment domain (CARD). NALPs are implicated in the activation of proinflammatory caspases (e.g., CASP1; MIM 147678) via their involvement in multiprotein complexes called inflammasomes (Tschopp et al., 2003 [PubMed 12563287]).[supplied by OMIM, Mar 2008],
  • Function: alternative products:Experimental confirmation may be lacking for some isoforms,function:May be involved in inflammation.,sequence caution:Translated as Gln.,similarity:Belongs to the NLRP family.,similarity:Contains 1 DAPIN domain.,similarity:Contains 1 NACHT domain.,similarity:Contains 8 LRR (leucine-rich) repeats.,
  • Species: Human;Rat;Mouse;
  • Range: WB;IHC
  • Protein: NALP4
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