• CNOT6 rabbit pAb
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YP-Ab-11731-100UL

CNOT6 rabbit pAb

CNOT6 rabbit pAb

Size
  • Gene Name: CNOT6 CCR4 KIAA1194
  • Immunogen: Synthesized peptide derived from human CNOT6 AA range: 293-343
  • Specificity: This antibody detects endogenous levels of CNOT6 at Human/Mouse/Rat
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: WB 1：500-2000
  • Purification process: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Background: This gene encodes the catalytic component of the CCR4-NOT core transcriptional regulation complex. The encoded protein has a 3'-5' RNase activity and prefers polyadenylated substrates. The CCR4-NOT complex plays a role in many cellular processes, including miRNA-mediated repression, mRNA degradation, and transcriptional regulation. [provided by RefSeq, Dec 2014],
  • Function: cofactor:Magnesium.,function:Poly(A) nuclease involved in mRNA decay mediated by the major-protein-coding determinant of instability (mCRD) of the FOS gene in the cytoplasm. Has 3'-5' RNase activity. The CCR4-NOT complex functions as general transcription regulation complex.,similarity:Belongs to the CCR4/nocturin family.,similarity:Contains 3 LRR (leucine-rich) repeats.,subunit:Subunit of the CCR4-NOT core complex that contains CHAF1A, CHAF1B, CNOT1, CNOT2, CNOT3, CNOT4, CNOT6 and CNOT8. Interacts with UNR.,
  • Species: Human; Mouse;Rat
  • Range: WB
  • Protein: CNOT6
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