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Upingbio

SKU(재고 관리 코드):YP-Ab-11927-100UL

ZMIZ2 rabbit pAb

ZMIZ2 rabbit pAb

Size
  • Gene Name: ZMIZ2 KIAA1886 ZIMP7 HRIHFB2007
  • Immunogen: Synthesized peptide derived from human ZMIZ2 AA range: 512-562
  • Specificity: This antibody detects endogenous levels of ZMIZ2 at Human/Mouse
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: WB 1:500-2000
  • Purification process: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Background: ZMIZ2 and ZMIZ1 (MIM 607159) are members of a PIAS (see MIM 603566)-like family of proteins that interact with nuclear hormone receptors. ZMIZ2 interacts with androgen receptor (AR; MIM 313700) and enhances AR-mediated transcription (Huang et al., 2005 [PubMed 16051670]).[supplied by OMIM, May 2010],
  • Function: domain:The C-terminal proline-rich domain possesses a significant intrinsic transcriptional activity. This activity is inhibited by the N-terminus in the full-length protein.,function:Increases ligand-dependent transcriptional activity of AR and other nuclear hormone receptors.,similarity:Contains 1 SP-RING-type zinc finger.,subcellular location:Detected at replication foci throughout S phase.,subunit:Interacts with AR, SMARCA4/BRG1 and SMARCE1/BAF57. Interaction with either SMARCA4 and SMARCE1 enhances AR-mediated transcription.,tissue specificity:Expressed most abundantly in testis with lower levels in heart, brain, pancreas, prostate and ovary.,
  • Species: Human; Mouse
  • Range: WB
  • Protein: ZMIZ2
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