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Upingbio
SKU(재고 관리 코드):YP-Ab-12300-100UL
DREB rabbit pAb
DREB rabbit pAb
- Gene Name: DBN1 D0S117E
- Immunogen: Synthesized peptide derived from human DREB AA range: 484-534
- Specificity: This antibody detects endogenous levels of DREB at Human/Mouse/Rat
- Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source: Polyclonal, Rabbit,IgG
- Dilution ratio: WB 1：500-2000
- Purification process: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
- Concentration: 1 mg/ml
- Storage: -20°C/1 year
- Background: The protein encoded by this gene is a cytoplasmic actin-binding protein thought to play a role in the process of neuronal growth. It is a member of the drebrin family of proteins that are developmentally regulated in the brain. A decrease in the amount of this protein in the brain has been implicated as a possible contributing factor in the pathogenesis of memory disturbance in Alzheimer's disease. At least two alternative splice variants encoding different protein isoforms have been described for this gene. [provided by RefSeq, Jul 2008],
- Function: function:Drebrins might play some role in cell migration, extension of neuronal processes and plasticity of dendrites, respectively.,similarity:Contains 1 ADF-H domain.,subunit:Binds F-actin.,tissue specificity:Brain neurons. Also found in the heart, placenta, skeletal muscle, kidney and pancreas.,
- Species: Human; Mouse;Rat
- Range: WB
- Protein: DREB
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