• RN213 rabbit pAb
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YP-Ab-12339-100UL

RN213 rabbit pAb

RN213 rabbit pAb

Size
  • Gene Name: RNF213 ALO17 C17orf27 KIAA1554 KIAA1618 MYSTR
  • Immunogen: Synthesized peptide derived from human RN213. AA range:307-407
  • Specificity: This antibody detects endogenous levels of RN213 at Human/Mouse
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: IHC-p 1：50-200. IF 1:50-200
  • Purification process: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Background: This gene encodes a protein containing a C3HC4-type RING finger domain, which is a specialized type of Zn-finger that binds two atoms of zinc and is thought to be involved in mediating protein-protein interactions. The protein also contains an AAA domain, which is associated with ATPase activity. This gene is a susceptibility gene for Moyamoya disease, a vascular disorder of intracranial arteries. This gene is also a translocation partner in anaplastic large cell lymphoma and inflammatory myofibroblastic tumor cases, where a t(2;17)(p23;q25) translocation has been identified with the anaplastic lymphoma kinase (ALK) gene on chromosome 2, and a t(8;17)(q24;q25) translocation has been identified with the MYC gene on chromosome 8. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2011],
  • Function: disease:A chromosomal aberration involving ALO17 is associated with anaplastic large-cell lymphoma (ALCL). Translocation t(2;17)(p23;q25) with ALK.,sequence caution:Translated as Gln.,similarity:Contains 1 RING-type zinc finger.,
  • Species: Human; Mouse
  • Range: IHC;IF
  • Protein: RN213
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