• LC3A rabbit pAb
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YP-Ab-12515-100UL

LC3A rabbit pAb

LC3A rabbit pAb

Size
  • Gene Name: MAP1LC3A
  • Immunogen: Synthesized peptide derived from human LC3A
  • Specificity: This antibody detects endogenous levels of Human LC3A
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
  • Purification process: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Other Names: Microtubule-associated proteins 1A/1B light chain 3A (Autophagy-related protein LC3 A;Autophagy-related ubiquitin-like modifier LC3 A;MAP1 light chain 3-like protein 1;MAP1A/MAP1B light chain 3 A;MAP1A/MAP1B LC3 A;Microtubule-associated protein 1 light chain 3 alpha)
  • Background: function:Probably involved in formation of autophagosomal vacuoles (autophagosomes).,PTM:The precursor molecule is cleaved by APG4B/ATG4B to form the cytosolic form, LC3-I. This is activated by APG7L/ATG7, transferred to ATG3 and conjugated to phospholipid to form the membrane-bound form, LC3-II.,similarity:Belongs to the MAP1 LC3 family.,subcellular location:LC3-II binds to the autophagic membranes.,subunit:3 different light chains, LC1, LC2 and LC3, can associate with MAP1A and MAP1B proteins.,tissue specificity:Most abundant in heart, brain, liver, skeletal muscle and testis but absent in thymus and peripheral blood leukocytes.,
  • Function: autophagic vacuole formation, proteolysis, autophagy, vacuole organization, macromolecule catabolic process, cellular response to starvation, response to extracellular stimulus, macroautophagy, modification-dependent protein catabolic process, protein catabolic process, response to nutrient levels, cellular response to extracellular stimulus, cellular response to nutrient levels, cellular response to stress, response to starvation, modification-dependent macromolecule catabolic process, cellular protein catabolic process, cellular macromolecule catabolic process,proteolysis involved in cellular protein catabolic process,
  • Species: Human;Rat;Mouse;
  • Range: WB;ELISA;IHC
  • Protein: LC3A
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