• EAT-2 Polyclonal Antibody
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YP-Ab-13919-100UL

EAT-2 Polyclonal Antibody

EAT-2 Polyclonal Antibody

Size
  • Gene Name: SH2D1B
  • Immunogen: The antiserum was produced against synthesized peptide derived from human SH2D1B. AA range:71-120
  • Specificity: EAT-2 Polyclonal Antibody detects endogenous levels of EAT-2 protein.
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: IHC: 1/100 - 1/300. ELISA: 1/40000.. IF 1:50-200
  • Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Other Names: SH2D1B; EAT2; SH2 domain-containing protein 1B; EWS/FLI1-activated transcript 2; EAT-2
  • Background: By binding phosphotyrosines through its free SRC (MIM 190090) homology-2 (SH2) domain, EAT2 regulates signal transduction through receptors expressed on the surface of antigen-presenting cells (Morra et al., 2001 [PubMed 11689425]).[supplied by OMIM, Mar 2008],
  • Function: function:Plays a role in controlling signal transduction through at least four receptors, CD84, CD150, CD229 and CD244, expressed on the surface of professional antigen-presenting cells.,similarity:Contains 1 SH2 domain.,subunit:Binds to the phosphorylated receptors CD84, CD150, CD229 and CD244. Does not bind to non-phosphorylated CD150.,
  • Species: Human;Rat;Mouse;
  • Range: IHC;IF;ELISA
  • Protein: SH2 domain-containing protein 1B
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