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Upingbio
SKU(재고 관리 코드):YP-Ab-15872-100UL
ALS Polyclonal Antibody
ALS Polyclonal Antibody
- Gene Name: IGFALS
- Immunogen: The antiserum was produced against synthesized peptide derived from human IGFALS. AA range:303-352
- Specificity: ALS Polyclonal Antibody detects endogenous levels of ALS protein.
- Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source: Polyclonal, Rabbit,IgG
- Dilution ratio: Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
- Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration: 1 mg/ml
- Storage: -20°C/1 year
- Other Names: IGFALS; ALS; Insulin-like growth factor-binding protein complex acid labile subunit; ALS
- Background: The protein encoded by this gene is a serum protein that binds insulin-like growth factors, increasing their half-life and their vascular localization. Production of the encoded protein, which contains twenty leucine-rich repeats, is stimulated by growth hormone. Defects in this gene are a cause of acid-labile subunit deficiency, which maifests itself in a delayed and slow puberty. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Mar 2009],
- Function: function:Involved in protein-protein interactions that result in protein complexes, receptor-ligand binding or cell adhesion.,similarity:Contains 20 LRR (leucine-rich) repeats.,subunit:Forms a ternary complex of about 140 to 150 kDa with IGF-I or IGF-II and IGFBP-3.,tissue specificity:Plasma.,
- Species: Human;Rat;Mouse;
- Range: WB;ELISA
- Protein: Insulin-like growth factor-binding protein complex acid labile subunit
- DA: 66kD
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