• ARHGEF10 Polyclonal Antibody
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YP-Ab-16138-100UL

ARHGEF10 Polyclonal Antibody

ARHGEF10 Polyclonal Antibody

Size
  • Gene Name: ARHGEF10
  • Immunogen: The antiserum was produced against synthesized peptide derived from human ARHGEF10. AA range:339-388
  • Specificity: ARHGEF10 Polyclonal Antibody detects endogenous levels of ARHGEF10 protein.
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/20000.. IF 1:50-200
  • Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Other Names: ARHGEF10; KIAA0294; Rho guanine nucleotide exchange factor 10
  • Background: This gene encodes a Rho guanine nucleotide exchange factor (GEF). Rho GEFs regulate the activity of small Rho GTPases by stimulating the exchange of guanine diphosphate (GDP) for guanine triphosphate (GTP) and may play a role in neural morphogenesis. Mutations in this gene are associated with slowed nerve conduction velocity (SNCV). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015],
  • Function: disease:Defects in ARHGEF10 are the cause of slowed nerve conduction velocity (SNCV) [MIM:608236]. Affected individuals present a reduction in nerve conduction velocities without any clinical signs of peripheral or central nervous system dysfunction. SNCV inheritance is autosomal dominant.,function:May play a role in developmental myelination of peripheral nerves.,sequence caution:Cloning artifact.,sequence caution:Translated as Lys.,similarity:Contains 1 DH (DBL-homology) domain.,
  • Species: Human;Monkey
  • Range: WB;IHC;IF;ELISA
  • Protein: Rho guanine nucleotide exchange factor 10
  • DA: 152kD
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