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Upingbio
SKU(재고 관리 코드):YP-Ab-16750-100UL
MCM4 Polyclonal Antibody
MCM4 Polyclonal Antibody
- Gene Name: MCM4
- Immunogen: The antiserum was produced against synthesized peptide derived from human MCM4. AA range:20-69
- Specificity: MCM4 Polyclonal Antibody detects endogenous levels of MCM4 protein.
- Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source: Polyclonal, Rabbit,IgG
- Dilution ratio: WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/20000.. IF 1:50-200
- Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration: 1 mg/ml
- Storage: -20°C/1 year
- Other Names: MCM4; CDC21; DNA replication licensing factor MCM4; CDC21 homolog; P1-CDC21
- Background: The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 6 and 7 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. The phosphorylation of this protein by CDC2 kinase reduces the DNA helicase activity and chromatin binding of the MCM complex. This gene is mapped to a region on the chromosome 8 head-to-head next to the PRKDC/DNA-PK, a DNA-activated protein kinase involved in the repair of DNA double-strand breaks. Alternatively spliced transcri
- Function: function:Involved in the control of DNA replication.,similarity:Belongs to the MCM family.,similarity:Contains 1 MCM domain.,
- Species: Human;Mouse
- Range: WB;IHC;IF;ELISA
- Protein: DNA replication licensing factor MCM4
- DA: 96kD
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