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Upingbio
SKU(재고 관리 코드):YP-Ab-17036-100UL
KALIG-1 Polyclonal Antibody
KALIG-1 Polyclonal Antibody
- Gene Name: KAL1
- Immunogen: The antiserum was produced against synthesized peptide derived from human KAL1. AA range:151-200
- Specificity: KALIG-1 Polyclonal Antibody detects endogenous levels of KALIG-1 protein.
- Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source: Polyclonal, Rabbit,IgG
- Dilution ratio: WB 1:500-2000;IHC-p 1:50-300
- Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration: 1 mg/ml
- Storage: -20°C/1 year
- Other Names: KAL1; ADMLX; KAL; KALIG1; Anosmin-1; Adhesion molecule-like X-linked; Kallmann syndrome protein
- Background: Mutations in this gene cause the X-linked Kallmann syndrome. The encoded protein is similar in sequence to proteins known to function in neural cell adhesion and axonal migration. In addition, this cell surface protein is N-glycosylated and may have anti-protease activity. [provided by RefSeq, Jul 2008],
- Function: disease:Defects in KAL1 are the cause of Kallmann syndrome type 1 (KAL1) [MIM:308700]; also known as hypogonadotropic hypogonadism and anosmia. Anosmia or hyposmia is related to the absence or hypoplasia of the olfactory bulbs and tracts. Hypogonadism is due to deficiency in gonadotropin-releasing hormone and probably results from a failure of embryonic migration of gonadotropin-releasing hormone-synthesizing neurons. In some patients other developmental anomalies can be present, which include renal agenesis, cleft lip and/or palate, selective tooth agenesis, and bimanual synkinesis. In some cases anosmia may be absent or inconspicuous.,function:May be an adhesion-like molecule with anti-protease activity.,PTM:N-glycosylated.,similarity:Contains 1 WAP domain.,similarity:Contains 4 fibronectin type-III domains.,
- Species: Human;Rat;Mouse;
- Range: WB;IHC
- Protein: Anosmin-1
- DA: 76kD
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