• METL8 rabbit pAb
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YP-Ab-17278-100UL

METL8 rabbit pAb

METL8 rabbit pAb

Size
  • Gene Name: METTL8
  • Immunogen: Synthesized peptide derived from human C-ternal METL8
  • Specificity: This antibody detects endogenous levels of METL8 at Human, Mouse
  • Composition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
  • Source: Rabbit,polyclonal
  • Dilution ratio: WB 1:500-2000 IHC 1:50-200
  • Purification process: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Other Names: Methyltransferase-like protein 8 (EC 2.1.1.-)
  • Function: Mitochondrial S-adenosyl-L-methionine-dependent methyltransferase that mediates N(3)-methylcytidine modification of residue 32 of the tRNA anticodon loop of mitochondrial tRNA(Ser)(UCN) and tRNA(Thr) . N(3)-methylcytidine methylation modification regulates mitochondrial translation efficiency and is required for activity of the respiratory chain . N(3)-methylcytidine methylation of mitochondrial tRNA(Ser)(UCN) requires the formation of N(6)-dimethylallyladenosine(37) (i6A37) by TRIT1 as prerequisite . May also mediate N(3)-methylcytidine modification of mRNAs . The existence of N(3)-methylcytidine modification on mRNAs is however unclear, and additional evidences are required to confirm the role of the N(3)-methylcytidine-specific mRNA methyltransferase activity of METTL8 in vivo .
  • Species: Human, Mouse
  • Range: IHC,WB
  • Protein: Methyltransferase-like protein 8 (EC 2.1.1.-)
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