• Phospho-IKK alpha (Thr23) Rabbit pAb
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YP-Ab-17826-100UL

Phospho-IKK alpha (Thr23) Rabbit pAb

Phospho-IKK alpha (Thr23) Rabbit pAb

Size
  • Gene Name: CHUK
  • Immunogen: Synthetic peptide of human CHUK
  • Dilution ratio: WB: 1/500-1/1000 IHC: 1/50-1/100
  • Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Other Names: CHUK; IKKA; TCF16; Inhibitor of nuclear factor kappa-B kinase subunit alpha; I-kappa-B kinase alpha; IKK-A; IKK-alpha; IkBKA; IkappaB kinase; Conserved helix-loop-helix ubiquitous kinase; I-kappa-B kinase 1; IKK1; Nuclear factor NF-kappa-B
  • Background: Plays an essential role in the NF-kappa-B signaling pathway which is activated by multiple stimuli such as inflammatory cytokines, bacterial or viral products, DNA damages or other cellular stresses. Activation of IKK depends upon phosphorylation at Ser177 and Ser181 in the activation loop of IKKβ (Ser176 and Ser180 in IKKα), which causes conformational changes, resulting in kinase activation.
  • Species: Human,Mouse,Rat
  • Range: WB,IHC-P
  • DA: Calculated MW: 85 kDa; Observed MW: 85 kDa
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